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It can get you high, just not as high (or it takes more to get as high). Trim used to be considered a waste product for a reason: While it contains cannabinoids, it doesn't have nearly as much as the buds themselves.You won't find edibles products advertising OG Kush brownies” or Sour Diesel Gumdrops” because the trim they buy is undifferentiated, so you can't count on any strain-specific effects with these products. Instead, manufacturers buy trim in bulk from multiple growers, who bag up the clippings without regard to strain or type. It may be theoretically possible to limit batches of trim to one strain, but that's not how it's done now.And not only does that trim not come from a single plant, it doesn't even come from the same strain or even the same sub-species, indica or sativa. Since the buds are desired in the smoking market, edibles manufacturers use the clippings from trimming—previously considered a waste product—to make their oils. But when you're consuming edibles, you're typically consuming your pot in the form of cannabis oils added to the food recipes.Or if you buy a big bag of weed, you're either getting buds from one plant or buds from plants that are the same variety (and are generally identical clones). When you smoke a bud of marijuana, you are smoking actual plant material from an actual, individual plant. Depending on the method of extraction, that process could alter the composition of the cannabinoids in a way that simply smoking them doesn't.When you smoke pot, the cannabinoids in it are decarboxylated—turned to smoke—when the flame ignites the bud, but with edibles, that decarboxylation has taken place long before, during the process of extracting the cannabinoids from the raw plant material. But in addition to differences in the rapidity of the onset of the high, the method of ingestion can cause changes in the quality of the high. First, when you smoke pot, the cannabinoids in it go into your lungs and thence directly into your bloodstream, getting that high-inducing THC into your system in a hurry, while if you eat it, it is digested and passed through the liver before entering the bloodstream.Edibles didn't go on sale in Washington state until mid-year last year, but they're reportedly going gangbusters up there, too. Click here to get your free daily email briefing today! FierceMedicalDevices provides breaking news and critical insights into the medical device and diagnostics industries, with a special emphasis on clinical studies, FDA/EMEA regulations, emerging technologies, and post-marketing.